Systemic lupus erythematosus–associated neutrophilic dermatosis with palmoplantar involvement

BMZ: basement membrane DEJ: dermoepidermal junction DIF: direct immunofluorescence LE: lupus erythematosus SLE: systemic lupus erythematosus INTRODUCTION Neutrophilic infiltrates in the setting of systemic lupus erythematosus (SLE) are commonly associated with bullous or vasculitic disease. Recently, an increasing number of reports describe a nonbullous, nonvasculitic SLE-associated neutrophilic dermatosis. Prior cases of SLE-associated neutrophilic dermatosis describe an urticarial eruption involving the trunk and extremities. Here we report the case of a 27-year-old woman with SLE-associated neutrophilic dermatosis with palmoplantar involvement, thus, expanding the clinical spectrum of this disease. Neutrophilic dermatosis may represent the initial cutaneous manifestation of systemic disease in onethird of patients. Thus, prompt recognition of this distinct cutaneous entity should promote screening for SLE.